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❑ Are you scheduled to acquire surgical procedures or other treatments that use anesthesia or deep sleepiness (deep sedation)?
Recommend sufferers who are making use of oral hormonal contraceptives change to a non-oral contraceptive process, or include a barrier way of contraception, for four weeks immediately after initiation with Zepbound and for 4 weeks following Each and every dose escalation. Zepbound delays gastric emptying, so it could make oral contraceptives significantly less powerful.1
Make sure the pen is within the locked posture, pull off The grey base cap, and toss it absent. Will not place it back on. Do not contact the needle.
Zepbound is contraindicated in people with a personal or loved ones history of MTC or in sufferers with Multiple Endocrine Neoplasia syndrome variety two (MEN 2). Counsel clients concerning the prospective threat for MTC with the use of Zepbound and advise them of signs of thyroid tumors (e.
Thigh: The outer region in the higher thigh is yet another choice for subcutaneous injection because of its effortless attain and fatty layer for quick absorption.
Acute Kidney Personal injury: Use of Zepbound has become linked to acute kidney personal injury, which can result from dehydration due to gastrointestinal adverse reactions to Zepbound, like nausea, vomiting, and diarrhea. In people taken care of with GLP-1 receptor agonists, there are postmarketing reviews of acute kidney harm and worsening of Long-term renal failure, which may at times need hemodialysis.
Zepbound is proven to help adults with obesity realize considerable weightloss and retain it very long term1
When you take the injection out on the refrigerator, Be certain that the padlock symbol close to the purple button shows ‘locked.’ In addition, Check out the expiration day, dose about the pen, and make sure the pen is clear.
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To administer the Zepbound injection, you to start with need to scrub the injection site. Fold the piece of apparel (if any) masking the injection site. Clean the site of injection by next these measures:
Consider therapy response and tolerability when picking routine maintenance dosage. Otherwise tolerated, consider a lessen servicing dosage
Now, switch over the needle and force it with the vial’s rubber stopper. Push the plunger to release the air in the syringe to the vial, rendering it easier zepbound injection to draw the medication into your syringe.
Risk of Thyroid C-mobile Tumors: Counsel sufferers regarding the probable risk for MTC with the usage of Zepbound and notify them of indicators of thyroid tumors (e.g., a mass during the neck, dysphagia, dyspnea, persistent hoarseness). Schedule checking of serum calcitonin or working with thyroid ultrasound is of uncertain price for early detection of MTC in individuals treated with Zepbound. This sort of monitoring may improve the danger of pointless techniques, a result of the small check specificity for serum calcitonin and also get more info a superior qualifications incidence of thyroid ailment.
It's crucial to keep the medication in accordance with the storage situations shared from the manufacturer to receive the utmost benefit. Below’s how you can retail outlet Zepbound: